Here are some of the options available to encrypt a SharePoint site :
- TDE – Transparent Data Encryption. – This option is only supported in SQL server Enterprise edition.
- BitLocker – Encryption on hard drive volume scope. – The main concern is performances and the fact that the whole drive is being encrypted.
- Application level encryption – Not supported in SharePoint.
- Third party products like Storage Point.
Please note that HIPAA requirements states that DBA won’t have access to the encrypted blub ( file/data ), one option is to use a third party tool like Storage point which move the data from SQL to a remote storage location and encrypt the blub.